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A homologous sequence-conservation screen against all possible transcripts that were independent of and not derived from angiotensinogen looking for similarities to AnglV identified partial homology with the hinge region of the plasminogen family of proteins, which include plasminogen itself, its anti-angiogenic degradation product, angiostatin, and the protein hormones heptocyte growth factor (HGF) and macrophage stimulating protein (MSP)

The samples were diluted by 100 times and measured using LCMS in the selective ion mode

10.1161/STROKEAHA.120.032736 Stroke 63 MaestriniI.TagzirtM.GautierS.DupontA.MendykA

It is a potent antioxidant with anti-inflammatory properties and has been shown to inhibit the release of histamine 15 from immune cells, making it a natural antihistamine

2011;342:d2616

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